Higher dose of erythropoietin for anemia correction in Balkan endemic nephropathy patients
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چکیده
منابع مشابه
Higher apoptotic cell rate in Balkan endemic nephropathy--stereologic analysis.
The aim of this study was to correlate apoptotic cell rate from different nephron segments between control group and groups of patients with Balkan endemic nephropathy (BEN). Kidney specimens of20 patients with clinically and epidemiologically confirmed BEN were compared with biopsy material of 10 patients (group I, non BEN) without glomerular or tubulointerstitial disease. Out of 20 patients w...
متن کاملThe pharmacokinetics of recombinant human erythropoietin in Balkan endemic nephropathy patients.
BACKGROUND Balkan endemic nephropathy (BEN) hemodialysis patients require a higher dose of recombinant human erythropoietin for maintaining target hemoglobin level than patients with other kidney diseases. OBJECTIVES Comparison of the pharmacokinetics of beta-erythropoietin given subcutaneously to hemodialysis patients with BEN or other kidney diseases (non-BEN). METHODS Recombinant human e...
متن کاملEndemic (Balkan) nephropathy is aristolochic acid nephropathy.
Endemic nephropathy is a syndrome that comprises two entities: chronic interstitial nephropathy and urothelial cell cancers predominantly of the upper urinary tract. The etiological agent for the disease is aristolochic acid, a compound found in the plants of Aristolochia spp. The development of urothelial cancers is characterized by the formation of aristolactam DNA adducts leading to mutation...
متن کاملEarly Screening of Balkan Endemic Nephropathy
Introduction Balkan endemic nephropathy (BEN) is a chronic irreversible interstitial sclerosis, for which over the last 25 years, chronic exposure to aristolochic acid from the contaminated cereal seeds has been considered the most likely cause. The aim of our research is to reevaluate trends of disease and to try to obtain new information about practical implementing of in-field screening of B...
متن کاملWeathered Coal Deposits and Balkan Endemic Nephropathy
The correlation between the geographic occurrence of Balkan endemic nephropathy (BEN) and low rank Pliocene lignites is striking. Comparison of mass spectra of methanol extracts from lignite samples collected in the vicinity of two endemic villages, with mass spectra of methanol extracts higher grade coals, shows the presence of many more potentially nephrotoxic compounds, and much higher total...
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ژورنال
عنوان ژورنال: Srpski arhiv za celokupno lekarstvo
سال: 2012
ISSN: 0370-8179,2406-0895
DOI: 10.2298/sarh1208456l